Santa Maria de Jesus Vacations from $661

Book a Hotel + Flight or Car together to unlock savings

Your Santa Maria de Jesus Vacation

Lock in a Santa Maria de Jesus vacation package and get set to experience this captivating city the easy way. Consider staying in the neighborhood of Santa Ana, which is good for culture and history. Make your trip to Santa Maria de Jesus even more exciting by including some sightseeing. Casa Santo Domingo Museum, Central Park and Santa Catalina Arch are among the most popular attractions you'll want to explore. Check out Expedia's extensive range of travel options and begin planning your dream vacation to Santa Maria de Jesus today.

The Latest Santa Maria de Jesus vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Soleil La Antigua

Hotel Soleil La Antigua

4 out of 5
Price was $946, price is now $661 per person
$661
per person
Sep 20 - Sep 23
found 3 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guatemala City (GUA)
8.6/10 Excellent! (1,000 reviews)
Pequeños inconvenientes al usar el sauna y spa, tuve que pedir cambio de toalla que se la tuve que pedir a un adolescente la había agarrado y la estaba usando, personas sin traje de baño usando el jacuzzi en ropa interior o pantaloneta. Los baños del spa se mantenían sucios por la cantidad de personas presentes por el finde largo. El primer día esperamos 1hr para que hubieran toallas disponibles.

Reviewed on Jun 29, 2026

Casa Faustina Boutique Hotel

Casa Faustina Boutique Hotel

4 out of 5
Save 100% on your flight
Price was $1,210, price is now $730 per person
$730
per person
Sep 9 - Sep 14
found 1 hour ago
Roundtrip flight included
Los Angeles (LAX) to Guatemala City (GUA)
8.8/10 Excellent! (118 reviews)
Muy bonito hotel, personal amable, fácil de llegar y precio acorde.

Reviewed on Jul 1, 2026

Kula Maya Boutique Hotel & Spa

Kula Maya Boutique Hotel & Spa

5 out of 5
Save 100% on your flight
Price was $1,262, price is now $862 per person
$862
per person
Sep 17 - Sep 22
found 24 hours ago
Roundtrip flight included
Los Angeles (LAX) to Guatemala City (GUA)
9.6/10 Exceptional! (158 reviews)
amazing views!!!! beautiful hotel very clean. the restaurant was wonderful too

Reviewed on Jun 19, 2026

Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul

3.5 out of 5
Save 100% on your flight
Price was $1,171, price is now $801 per person
$801
per person
Aug 22 - Aug 29
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Guatemala City (GUA)
8.6/10 Excellent! (90 reviews)

Villas La Mar

Villas La Mar

4 out of 5
Price was $1,528, price is now $1,116 per person
$1,116
per person
Aug 14 - Aug 17
found 3 hours ago
Roundtrip flight included
New York (NYC) to Guatemala City (GUA)
8.2/10 Very Good! (146 reviews)
La Mar is a wonderful destination for a family escape!

Reviewed on Apr 7, 2026

Don't see what you're looking for?
See all available trips from Columbus to Santa Maria de Jesus
View all trips

What to do in Santa Maria de Jesus

Antigua: ATV Guided Sunset Tour

Antigua: ATV Guided Sunset Tour

$65
per adult
100% of travellers recommend
Antigua: ATV Guided Sunset Tour
From Antigua: 2-Day Acatenango Volcano Hiking Tour with Food

From Antigua: 2-Day Acatenango Volcano Hiking with Guide

$57
per adult
From Antigua: 2-Day Acatenango Volcano Hiking with Guide
Picture 5 for Activity From Antigua: Pacaya Volcano Trek

From Antigua: Pacaya Volcano Trek

$24
per adult
90% of travellers recommend
From Antigua: Pacaya Volcano Trek
See all activities in Santa Maria de Jesus

Santa Maria de Jesus Hotel Deals

Barceló Guatemala City

Barceló Guatemala City

4.5 out of 5
7 Avenida 15-45, Zona 9 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $117 total per night from Jul 12 to Jul 13
$117 total
Jul 12 - Jul 13
Total with taxes and fees
9.2/10 Wonderful! (3,289 reviews)
"La proprete était très bien et le lieu est très sécuritaire, par contre je n’apprécie pas le fait que la porte de la toilette de se barre pas."

Reviewed on Jun 30, 2026

Barceló Guatemala City
Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center

4.5 out of 5
Calzada Roosevelt 22-43 Guatemala City Guatemala
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $132 total per night from Jul 12 to Jul 13
$132 total
Jul 12 - Jul 13
Total with taxes and fees
9.2/10 Wonderful! (1,011 reviews)
"."

Reviewed on Jul 2, 2026

Tikal Futura Hotel & Convention Center
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
$271 nightly
The price is $331 total per night from Jul 5 to Jul 6
$331 total
Jul 5 - Jul 6
Total with taxes and fees
9.2/10 Wonderful! (1,068 reviews)
"Cleanliness and friendly staff"

Reviewed on Jul 1, 2026

Hotel Museo Spa Casa Santo Domingo
See all 1,266 properties in Santa Maria de Jesus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria de Jesus Vacation Packages

Santa Maria de Jesus Essential Information

Language
Spanish
Currency
Guatemalan quetzals
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
La Aurora Intl. Airport (GUA)
Population
15,500
Top Sights
Antigua Guatemala Cathedral, Volcan de Fuego and Volcan de Agua

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santa Maria de Jesus vacation package cost?
You can pick up a vacation package to this top destination from $661 on Expedia. But how much your vacation to Santa Maria de Jesus costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Maria de Jesus?
December, January and February are the best times to look for cheap Santa Maria de Jesus vacation packages. Opting to travel in quieter months means you can usually find lower prices on flights and hotels.
How many days is enough for Santa Maria de Jesus?
The ideal duration of your Santa Maria de Jesus vacation depends on what you'd like to see and do. Usually, a handful of days to a week will give you plenty of time to tick off all the major sights and explore some hidden spots along the way.
How to find the best Santa Maria de Jesus package deals?
Begin your search for a Santa Maria de Jesus package deal by entering your preferred travel dates and destination under our "Packages" tab. Then select a few filters, like "Popular locations" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santa Maria de Jesus package deal right away, just play around with your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Maria de Jesus adventure off to a flying start.
Is it cheaper to book a Santa Maria de Jesus vacation as a package?
You can enjoy significant savings on your next Santa Maria de Jesus getaway by booking a customized vacation package. Check the "Package" heading, then enter your travel dates and destination to browse the best airfares and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Santa Maria de Jesus?
If you've got your Santa Maria de Jesus vacation dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are perfect for impromptu escapes.
How to plan a trip to Santa Maria de Jesus?

  1. Choose your travel dates: What you'd like to do in Santa Maria de Jesus and your favorite season can help you decide when to go.
  2. Set your budget: Consider costs such as transportation, flights and meals when calculating how much to put aside for your trip to Santa Maria de Jesus. Then, select a property that suits your budget, whether that's a wallet-friendly stay or a more upscale getaway.
  3. Use our trip planning tool to discover Santa Maria de Jesus: Research every aspect of your trip to Santa Maria de Jesus with this handy planner. Invite family or friends to collaborate on a group trip, search for hotels or things to do and make bookings.
  4. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Santa Maria de Jesus. Then, estimate how long you'll need for each, including any travel time.
  5. Combine your flights and hotel: Awesome destination, check. Length of stay, check. All that's left is to pick a Santa Maria de Jesus vacation package that brings all your bookings together.
  6. Book experiences or activities ahead of time: Whether it's entrance to a major attraction or a walking tour, you won't have to worry about missing out on Santa Maria de Jesus's highlights. Find all the fun things to do in Santa Maria de Jesus with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later Santa Maria de Jesus vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Santa Maria de Jesus vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.